Major Ethnic Populations Are Significantly Differentiated at the Glioblastoma Multiforme Candidate Loci.

Abstract excerpt

Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor, with well-documented incidence disparities across ethnic populations: highest in Europeans and lowest in East Asians and Africans. Still, the genetic basis of these differences remains poorly understood. This study assessed whether population-level differences in GBM risk allele frequencies correlate with ethnic disparities in prevalence....

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