Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for a hereditary neuroblastoma predisposition locus at chromosome 16p12-13.

Cancer research - 15 Nov 2002

Maris John M, Weiss Matthew J, Mosse Yael, Hii George, Guo Chun, White Peter S, Hogarty Michael D, Mirensky Tamar, Brodeur Garrett M, Rebbeck Timothy R, Urbanek Margrit, Shusterman Suzanne

Abstract excerpt

Hereditary predisposition to develop neuroblastoma (Online Mendelian Inheritance in Man 256700), a pediatric cancer of the sympathetic nervous system, segregates as an autosomal dominant Mendelian trait. We performed linkage analysis on seven families with two or more first-degree relatives affec...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Gland Neoplasms
Share to Child, Preschool
Share to Chromosomes, Human, Pair 16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Genome, Human

Share to Infant

Share to Loss of Heterozygosity

Share to Neuroblastoma

Source

Identifiers

PMID: 12438263

Genes

MAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12438263-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for a hereditary neuroblastoma predisposition locus at chromosome 16p12-13.PMID 12438263Read ↗

Localization of a hereditary neuroblastoma predisposition gene to 16p12-p13.Semantic proximity Read ↗

Genetic predisposition to familial neuroblastoma: identification of two novel genomic regions at 2p and 12p.Semantic proximity Read ↗

Genetic susceptibility to neuroblastoma.Semantic proximity Read ↗

Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma.Semantic proximity Read ↗

Weak linkage at 4p16 to predisposition for human neuroblastoma.Semantic proximity Read ↗

Inherited rare variants in homologous recombination and neurodevelopmental genes are associated with increased risk of neuroblastoma.Semantic proximity Read ↗

Novel regions of chromosomal loss in familial neuroblastoma by comparative genomic hybridizationSemantic proximity Read ↗

Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma.Semantic proximity Read ↗

Detailed deletion mapping of chromosome band 14q32 in human neuroblastoma defines a 1.1-Mb region of common allelic loss.Semantic proximity Read ↗

Chromosome 6p22 locus associated with clinically aggressive neuroblastoma.Semantic proximity Read ↗

A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3.Semantic proximity Read ↗

Analysis of neuroblastoma tumour progression; loss of PHOX2B on 4p13 and 17q gain are early events in neuroblastoma tumourigenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.