Article
Genetic Analysis in African American Children Supports Ancestry-Specific Neuroblastoma Susceptibility.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2022
Testori Alessandro, Vaksman Zalman, Diskin Sharon J, Hakonarson Hakon, Capasso Mario, Iolascon Achille, Maris John M, Devoto Marcella
Abstract excerpt
BACKGROUND: Neuroblastoma is rarer in African American (AA) children compared with American children of European descent. AA children affected with neuroblastoma, however, more frequently develop the high-risk form of the disease. METHODS: We have genotyped an AA cohort of 629 neuroblastoma cases (254 high-risk) and 2,990 controls to investigate genetic susceptibility to neuroblastoma in AAs. RESULTS: We...
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