Article
Leukocyte telomere length-related genetic variants in 1p34.2 and 14q21 loci contribute to the risk of esophageal squamous cell carcinoma.
International journal of cancer - 15 Jun 2013
Shi Juan, Sun Fang, Peng Li, Li Bo, Liu Li, Zhou Changchun, Han Jianjun, Zhang Li, Zhou Liqing, Zhang Xiaojiao, Pu Honglei, Tong Lei, Yuan Qipeng, Song Xianrang, Yang Ming
Abstract excerpt
Short leukocyte telomere length has been associated with significantly increased risk of esophageal cancer. A previous genome-wide association study demonstrated that four SNPs (rs398652 on 14q21, rs621559 on 1p34.2, rs6028466 on 20q11.22 and rs654128 on 6q22.1) were associated with leukocyte telomere length in Caucasians. However, the role of these genetic variants on esophageal squamous cell carcinoma (ESCC)...
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