Article
Leukocyte telomere length-related rs621559 and rs398652 genetic variants influence risk of HBV-related hepatocellular carcinoma.
PloS one - 1 Jan 2014
Pan Wenting, Cheng Guangxia, Xing Huaixin, Shi Juan, Lu Chao, Wei Jinyu, Li Lichao, Zhou Changchun, Yuan Qipeng, Zhou Liqing, Yang Ming
Abstract excerpt
Recent genome-wide association studies (GWAS) have identified eleven leukocyte telomere length (LTL)-related single nucleotide polymorphisms (SNPs). Since LTL has been associated with risk of many malignancies, LTL-related SNPs may contribute to cancer susceptibility. To test this hypothesis in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), we genotyped these eleven LTL-related SNPs in a...
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