Article
U-shaped association between telomere length and esophageal squamous cell carcinoma risk: a case-control study in Chinese population.
Frontiers of medicine - 1 Dec 2015
Du Jiangbo, Xue Wenjie, Ji Yong, Zhu Xun, Gu Yayun, Zhu Meng, Wang Cheng, Gao Yong, Dai Juncheng, Ma Hongxia, Jiang Yue, Chen Jiaping, Hu Zhibin, Jin Guangfu, Shen Hongbing
Abstract excerpt
Telomeres play a critical role in biological ageing by maintaining chromosomal integrity and preventing chromosome ends fusion. Epidemiological studies have suggested that inter-individual differences of telomere length could affect predisposition to multiple cancers, but evidence regarding esophageal squamous cell carcinoma (ESCC) was still uncertain. Several telomere length-related single nucleotide...
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