Article
Telomere length, genetic variants and gastric cancer risk in a Chinese population.
Carcinogenesis - 1 Sept 2015
Du Jiangbo, Zhu Xun, Xie Cuiwei, Dai Ningbin, Gu Yayun, Zhu Meng, Wang Cheng, Gao Yong, Pan Feng, Ren Chuanli, Ji Yong, Dai Juncheng, Ma Hongxia, Jiang Yue, Chen Jiaping, Yi Honggang, Zhao Yang, Hu Zhibin, Shen Hongbing, Jin Guangfu
Abstract excerpt
Telomeres maintain chromosomal stability and integrity and are crucial in carcinogenesis. Telomere length is implicated in multiple cancer risk, but the results are conflicting. Genome-wide association studies have identified several genetic loci associated with telomere length in Caucasians. However, the roles of telomere length and related variants on gastric cancer development are largely unknown. We conducted...
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