Article
Telomere length, genetic variants and risk of squamous cell carcinoma of the head and neck in Southeast Chinese.
Scientific reports - 9 Feb 2016
Gu Yayun, Yu Chengxiao, Miao Limin, Wang Lihua, Xu Chongquan, Xue Wenjie, Du Jiangbo, Yuan Hua, Dai Juncheng, Jin Guangfu, Hu Zhibin, Ma Hongxia, Shen Hongbing
Abstract excerpt
Telomere dysfunction participates in malignant transformation and tumorigenesis. Previous studies have explored the associations between telomere length (TL) and cancer susceptibility; however, the findings are inconclusive. The associations between genetic variants and TL have been verified by quite a few genome-wide association studies (GWAS). Yet, to date, there was no published study on the relationship...
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