Article
1p34.2 rs621559 and 14q21 rs398652 leukocyte telomere length-related genetic variants contribute to glioma susceptibility.
Journal of neuro-oncology - 1 Aug 2014
Chen Yi-Dong, Lu Chao, Wei Jinyu, Han Sichong, Wang Herui, Jiang Tao, Qiu Xiao-Guang, Yang Ming
Abstract excerpt
Recent genome-wide association studies have identified several leukocyte telomere length (LTL)-related single nucleotide polymorphisms (SNPs). Our previous data demonstrated that two SNPs (rs398652 on 14q21 and rs621559 on 1p34.2) were associated with LTL and risk of esophageal squamous cell carcinoma in Chinese. However, the role of these genetic variants on glioma risk is still unknown. Therefore, we examined...
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