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Article

Shortened telomere length is associated with increased risk of cancer: a meta-analysis.

PloS one - 1 Jan 2011

Ma Hongxia, Zhou Ziyuan, Wei Sheng, Liu Zhensheng, Pooley Karen A, Dunning Alison M, Svenson Ulrika, Roos Göran, Hosgood H Dean, Shen Min, Wei Qingyi

Abstract excerpt

BACKGROUND: Telomeres play a key role in the maintenance of chromosome integrity and stability, and telomere shortening is involved in initiation and progression of malignancies. A series of epidemiological studies have examined the association between shortened telomeres and risk of cancers, but the findings remain conflicting. METHODS: A dataset composed of 11,255 cases and 13,101 controls from 21 publications...

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Identifiers

PMID: 21695195
DOI: 10.1371/journal.pone.0020466
PMCID: PMC3112149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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