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Article

Programmed death-1 ligand-1 gene rs2890658 polymorphism associated with the risk of esophageal squamous cell carcinoma in smokers.

Cancer biomarkers : section A of Disease markers - 12 Dec 2017

Zhou Rong-Miao, Li Yan, Liu Jiang-Hui, Wang Na, Huang Xi, Cao Shi-Ru, Shan Bao-En

Abstract excerpt

BACKGROUND: The most important anti-tumor immune response is mediated by T lymphocytes. The interaction of programmed death-1 ligand-1 (PD-L1) with its receptor provides an inhibitory signal in T lymphocytes activation and proliferation. OBJECTIVE: This study aimed to investigate whether polymorphisms of PD-L1 were associated with the risk and prognosis of esophageal squamous cell carcinoma (ESCC) in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29060926
DOI: 10.3233/CBM-170269
PMCID: PMC13075744

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