Article
Genetic variants affecting telomere length are associated with the prognosis of esophageal squamous cell carcinoma in a Chinese population.
Molecular carcinogenesis - 1 Mar 2017
Lu Yue, Yan Caiwang, Du Jiangbo, Ji Yong, Gao Yong, Zhu Xun, Yu Fei, Huang Tongtong, Dai Juncheng, Ma Hongxia, Jiang Yue, Chen Jiaping, Shen Hongbing, Jin Guangfu, Yin Yongmei, Hu Zhibin
Abstract excerpt
Telomeres are essential for maintaining chromosomal stability and are crucial in tumor progression. Previous studies have explored the associations between telomere length and cancer prognosis, but the findings are inconclusive. Genome-wide association studies have identified several genetic variants associated with telomere length in Caucasians. However, the roles of telomere length and related genetic variants...
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