Article
Combined effects of leukocyte telomere length, p53 polymorphism and human papillomavirus infection on esophageal squamous cell carcinoma in a Han Chinese population.
Cancer epidemiology - 1 Oct 2014
Yu Qianqian, Yang Ju, Liu Bo, Li Wen, Hu Guangyuan, Qiu Hong, Huang Liu, Xiong Huihua, Yuan Xianglin
Abstract excerpt
Telomere shortening has been suggested to be a genetic predictor for various cancers. However, evidences about this point with respect to esophageal squamous cell carcinoma (ESCC) in Han Chinese populations remain limited. Our previous study demonstrated that p53 Arg72Pro polymorphism was associated with the risk of human papillomavirus (HPV)-related ESCC. Telomeres and p53 play important roles in maintaining...
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