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Article

Gene-nutrient interactions on the phosphoenolpyruvate carboxykinase influence insulin sensitivity in metabolic syndrome subjects.

Clinical nutrition (Edinburgh, Scotland) - 1 Aug 2013

Perez-Martinez Pablo, Garcia-Rios Antonio, Delgado-Lista Javier, Gjelstad Ingrid M F, Gibney James, Kieć-Wilk Beata, Camargo Antonio, Helal Olfa, Karlström Brita, Blaak Ellen E, Hall Wendy, Risérus Ulf, Dembińska-Kieć Aldona, Defoort Catherine, Saris Wim H M, Lovegrove Julie A, Drevon Christian A, Roche Helen M, Lopez-Miranda Jose

Abstract excerpt

BACKGROUND & AIMS: Genetic background may interact with habitual dietary fat composition, and affect development of the metabolic syndrome (MetS). The phosphoenolpyruvate carboxykinase gene (PCK1) plays a significant role regulating glucose metabolism, and fatty acids are key metabolic regulators, which interact with transcription factors and influence glucose metabolism. We explored genetic variability at the...

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Source

Identifiers

PMID: 23092637
DOI: 10.1016/j.clnu.2012.10.003

Genes

PCK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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