Article
ACC2 gene polymorphisms, metabolic syndrome, and gene-nutrient interactions with dietary fat.
Journal of lipid research - 1 Dec 2010
Phillips Catherine M, Goumidi Louisa, Bertrais Sandrine, Field Martyn R, Cupples L Adrienne, Ordovas Jose M, McMonagle Jolene, Defoort Catherine, Lovegrove Julie A, Drevon Christian A, Blaak Ellen E, Kiec-Wilk Beata, Riserus Ulf, Lopez-Miranda Jose, McManus Ross, Hercberg Serge, Lairon Denis, Planells Richard, Roche Helen M
Abstract excerpt
Acetyl-CoA carboxylase β (ACC2) plays a key role in fatty acid synthesis and oxidation pathways. Disturbance of these pathways is associated with impaired insulin responsiveness and metabolic syndrome (MetS). Gene-nutrient interactions may affect MetS risk. This study determined the relationship between ACC2 polymorphisms (rs2075263, rs2268387, rs2284685, rs2284689, rs2300453, , , , and...
