Article
Association of a polymorphism in the gene encoding phosphoenolpyruvate carboxykinase 1 with high-density lipoprotein and triglyceride levels.
Diabetologia - 1 Oct 2005
Shin H D, Park B L, Kim L H, Cheong H S, Kim J H, Cho Y M, Lee H K, Park K S
Abstract excerpt
AIMS/HYPOTHESIS: Phosphoenolpyruvate carboxykinase (PCK) is the key enzyme involved in the regulation of gluconeogenesis. The aim of this study was to identify genetic polymorphisms in potential candidate genes for type 2 diabetes by sequencing all exons in the PCK genes (PCK1 and PCK2), and examining the association with type 2 diabetes and diabetic phenotypes in a Korean population (775 type 2 diabetic patients...
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