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Article

Polyunsaturated Fatty Acids Modulate the Association between PIK3CA-KCNMB3 Genetic Variants and Insulin Resistance.

PloS one - 1 Jan 2013

Zheng Ju-Sheng, Arnett Donna K, Parnell Laurence D, Lee Yu-Chi, Ma Yiyi, Smith Caren E, Richardson Kris, Li Duo, Borecki Ingrid B, Tucker Katherine L, Ordovás José M, Lai Chao-Qiang

Abstract excerpt

BACKGROUND: Neighboring genes PIK3CA and KCNMB3 are both important for insulin signaling and β-cell function, but their associations with glucose-related traits are unclear. OBJECTIVE: The objective was to examine associations of PIK3CA-KCNMB3 variants with glucose-related traits and potential interaction with dietary fat. DESIGN: We first investigated genetic associations and their modulation by dietary fat in...

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Share to Class I Phosphatidylinositol 3-Kinases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23826284
DOI: 10.1371/journal.pone.0067394
PMCID: PMC3694924

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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