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Article

Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome.

Journal of lipid research - 1 Jul 2010

Phillips Catherine M, Goumidi Louisa, Bertrais Sandrine, Field Martyn R, Cupples L Adrienne, Ordovas Jose M, Defoort Catherine, Lovegrove Julie A, Drevon Christian A, Gibney Michael J, Blaak Ellen E, Kiec-Wilk Beata, Karlstrom Britta, Lopez-Miranda Jose, McManus Ross, Hercberg Serge, Lairon Denis, Planells Richard, Roche Helen M

Abstract excerpt

Long-chain acyl CoA synthetase 1 (ACSL1) plays an important role in fatty acid metabolism and triacylglycerol (TAG) synthesis. Disturbance of these pathways may result in dyslipidemia and insulin resistance, hallmarks of the metabolic syndrome (MetS). Dietary fat is a key environmental factor tha...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20176858
DOI: 10.1194/jlr.M003046
PMCID: PMC2882737

Genes

ACSL1
MAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20176858-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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