Article
The dietary monounsaturated to saturated fatty acid ratio modulates the genetic effects of GCKR on serum lipid levels in children.
Clinica chimica acta; international journal of clinical chemistry - 23 Oct 2015
Lee Hye-Ja, Jang Han Byul, Kim Hyo-Jin, Ahn Younjhin, Hong Kyung-Won, Cho Seong Beom, Kang Jae Heon, Park Sang Ick
Abstract excerpt
BACKGROUND: Glucokinase regulator (GCKR) plays important roles in the regulation of glucokinase (GK) activity and the metabolism of glucose and lipids. We investigated whether the association between GCKR genetic variants with serum lipids in Korean adults is replicated in children, and whether these genetic influences might be modulated by dietary monounsaturated fatty acid relative to saturated fatty acid...
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