Article

Obesity-Associated Genetic Variants and AMPK Signaling in Cardiovascular Disease: A Systematic Review of Mechanisms and Clinical Implications

2025-10-07

Abstract excerpt

<h4>Objective</h4> To investigate how genetic variations in obesity-related genes affect the AMPK signaling pathway and contribute to the pathophysiology of cardiovascular disease in the context of obesity. <h4>Background</h4> The global rise in obesity presents serious public health challenges, significantly increasing the risk of comorbidities such as type 2 diabetes and cardiovascular disease. Genetic predisp...

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Literature Corpus work: da8e2ba8-4f5f-582d-b232-5e220397b852
DOI: 10.1101/2025.10.04.25337310

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