Article
Calpain-10 interacts with plasma saturated fatty acid concentrations to influence insulin resistance in individuals with the metabolic syndrome.
The American journal of clinical nutrition - 1 May 2011
Perez-Martinez Pablo, Delgado-Lista Javier, Garcia-Rios Antonio, Ferguson Jane F, Gulseth Hanne L, Williams Christine M, Karlström Brita, Kieć-Wilk Beata, Blaak Ellen E, Helal Olfa, Małczewska-Malec Malgorzata, Defoort Catherine, Risérus Ulf, Saris Wim H, Lovegrove Julie A, Drevon Christian A, Roche Helen M, Lopez-Miranda Jose
Abstract excerpt
BACKGROUND: Calpain-10 protein (intracellular Ca(2+)-dependent cysteine protease) may play a role in glucose metabolism, pancreatic β cell function, and regulation of thermogenesis. Several CAPN10 polymorphic sites have been studied for their potential use as risk markers for type 2 diabetes and...
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