Article
Complement component 3 polymorphisms interact with polyunsaturated fatty acids to modulate risk of metabolic syndrome.
The American journal of clinical nutrition - 1 Dec 2009
Phillips Catherine M, Goumidi Louisa, Bertrais Sandrine, Ferguson Jane F, Field Martyn R, Kelly Enda D, Peloso Gina M, Cupples L Adrienne, Shen Jian, Ordovas Jose M, McManus Ross, Hercberg Serge, Portugal Henri, Lairon Denis, Planells Richard, Roche Helen M
Abstract excerpt
BACKGROUND: Complement component 3 (C3) is a novel determinant of the metabolic syndrome (MetS). Gene-nutrient interactions with dietary fat may affect MetS risk. OBJECTIVES: The objectives were to determine the relation between C3 polymorphisms and MetS and whether interaction with plasma polyunsaturated fatty acids (PUFAs), a biomarker of dietary PUFA, modulate this relation. DESIGN: C3 polymorphisms...
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