Article
Top single nucleotide polymorphisms affecting carbohydrate metabolism in metabolic syndrome: from the LIPGENE study.
The Journal of clinical endocrinology and metabolism - 1 Feb 2014
Delgado-Lista Javier, Perez-Martinez Pablo, Solivera Juan, Garcia-Rios Antonio, Perez-Caballero A I, Lovegrove Julie A, Drevon Christian A, Defoort Catherine, Blaak Ellen E, Dembinska-Kieć Aldona, Risérus Ulf, Herruzo-Gomez Ezequiel, Camargo Antonio, Ordovas Jose M, Roche Helen, Lopez-Miranda José
Abstract excerpt
RATIONALE: Metabolic syndrome (MetS) is a high-prevalence condition characterized by altered energy metabolism, insulin resistance, and elevated cardiovascular risk. OBJECTIVES: Although many individual single nucleotide polymorphisms (SNPs) have been linked to certain MetS features, there are few studies analyzing the influence of SNPs on carbohydrate metabolism in MetS. METHODS: A total of 904 SNPs (tag SNPs...
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