Article
Detection of loci for allergic asthma using SMXA recombinant inbred strains of mice.
Immunogenetics - 1 Jan 2013
Ohno Tamio, Okamoto Masakazu, Hara Toru, Hashimoto Naozumi, Imaizumi Kazuyoshi, Matsushima Miyoko, Nishimura Masahiko, Shimokata Kaoru, Hasegawa Yoshinori, Kawabe Tsutomu
Abstract excerpt
Asthma is regarded as a multifactorial inflammatory disorder arising as a result of inappropriate immune responses in genetically susceptible individuals to common environmental antigens. However, the precise molecular basis is unknown. To identify genes for susceptibility to three asthma-related traits, airway hyperresponsiveness (AHR), eosinophil infiltration, and allergen-specific serum IgE levels, we...
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