Article
Genetics of native airway responsiveness in mice.
American journal of respiratory and critical care medicine - 1 Oct 1997
De Sanctis G T, Drazen J M
Abstract excerpt
The inbred mouse represents a powerful tool for dissecting both simple and complex traits. Genetic studies in the mouse should identify disease genes acting in the same biochemical pathway as in the human. Problems associated with genetic heterogeneity, inability to control environmental conditions, lack of an abundant supply of genetic markers, and ethical considerations regarding human genetic crosses are but...
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