Article
Genetics of airway hyperresponsiveness.
The Journal of allergy and clinical immunology - 1 Jul 2001
De Sanctis G T, Daheshia M, Daser A
Abstract excerpt
Asthma is a disease characterized by intermittent airway obstruction, inflammatory cell infiltrates, increased mucus production, lung epithelial remodeling, and airway hyperreactivity. The genetics of asthma, as investigated in animal models, is poorly understood. Because no animal model of asthma mimics all of the pathologic and physiological features of asthma, genetic studies have focused on several...
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