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Article

Mapping cis-acting regulatory variation in recombinant congenic strains.

Physiological genomics - 13 Apr 2006

Lee Peter D, Ge Bing, Greenwood Celia M T, Sinnett Donna, Fortin Yannick, Brunet Sebastien, Fortin Anny, Takane Marina, Skamene Emil, Pastinen Tomi, Hallett Michael, Hudson Thomas J, Sladek Robert

Abstract excerpt

We present an integrated approach for the enriched detection of genes subject to cis-acting variation in the mouse genome. Gene expression profiling was performed with lung tissue from a panel of recombinant congenic strains (RCS) derived from A/J and C57BL/6J inbred mouse strains. A multiple-regression model measuring the association between gene expression level, donor strain of origin (DSO), and predominant...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16449383
DOI: 10.1152/physiolgenomics.00168.2005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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