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Article

Detection for gene-gene co-association via kernel canonical correlation analysis.

BMC genetics - 8 Oct 2012

Yuan Zhongshang, Gao Qingsong, He Yungang, Zhang Xiaoshuai, Li Fangyu, Zhao Jinghua, Xue Fuzhong

Abstract excerpt

BACKGROUND: Currently, most methods for detecting gene-gene interaction (GGI) in genomewide association studies (GWASs) are limited in their use of single nucleotide polymorphism (SNP) as the unit of association. One way to address this drawback is to consider higher level units such as genes or regions in the analysis. Earlier we proposed a statistic based on canonical correlations (CCU) as a gene-based method...

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PMID: 23039928
DOI: 10.1186/1471-2156-13-83
PMCID: PMC3506484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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