Article
A gene-based method for detecting gene-gene co-association in a case-control association study.
European journal of human genetics : EJHG - 1 May 2010
Peng Qianqian, Zhao Jinghua, Xue Fuzhong
Abstract excerpt
Association study (especially the genome-wide association study) now has a key function in identification and characterization of disease-predisposing genetic variant(s), which customarily involve multiple single nucleotide polymorphisms (SNPs) in a candidate region or across the genome. Case-control association design remains the most popular and a challenging issue in the statistical analysis is the optimal use...
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