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Article

A PLSPM-based test statistic for detecting gene-gene co-association in genome-wide association study with case-control design.

PloS one - 1 Jan 2013

Zhang Xiaoshuai, Yang Xiaowei, Yuan Zhongshang, Liu Yanxun, Li Fangyu, Peng Bin, Zhu Dianwen, Zhao Jinghua, Xue Fuzhong

Abstract excerpt

For genome-wide association data analysis, two genes in any pathway, two SNPs in the two linked gene regions respectively or in the two linked exons respectively within one gene are often correlated with each other. We therefore proposed the concept of gene-gene co-association, which refers to th...

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PMID: 23620809
DOI: 10.1371/journal.pone.0062129
PMCID: PMC3631168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23620809-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

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