Article
Analysis of gene-gene interactions using gene-trait similarity regression.
Human heredity - 1 Jan 2014
Wang Xin, Epstein Michael P, Tzeng Jung-Ying
Abstract excerpt
OBJECTIVE: Gene-gene interactions (G×G) are important to study because of their extensiveness in biological systems and their potential in explaining missing heritability of complex traits. In this work, we propose a new similarity-based test to assess G×G at the gene level, which permits the stu...
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