Article
Sparse generalized canonical correlation analysis for biological model integration: a genetic study of psychiatric disorders.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jan 2013
Kang Mingon, Zhang Baoju, Wu Xiaoyong, Liu Chunyu, Gao Jean
Abstract excerpt
In the post-genomic era, unveiling causal traits in the complex mechanisms that involve a number of diseases has been highlighted as one of the key goals. Much research has recently suggested integrative approaches of both genomewide association studies (GWAS) and gene expression profiling-based studies provide greater insight of the mechanism than utilizing only one. In this paper, we propose a novel method,...
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