Article
Haplotype-based interaction of the PPARGC1A and UCP1 genes is associated with impaired fasting glucose or type 2 diabetes mellitus.
Medicine - 1 Jun 2017
Pei Xiaoting, Liu Li, Cai Jialin, Wei Wenkai, Shen Yan, Wang Yaxuan, Chen Yanzi, Sun Panpan, Imam Mustapha Umar, Ping Zhiguang, Fu Xiaoli
Abstract excerpt
The aim of this study is to evaluate the effect of single-nucleotide polymorphisms (SNPs) of the PPARGC1A and UCP1 genes on impaired fasting glucose (IFG) or type 2 diabetes mellitus (T2DM) and the haplotype-based interaction between these genes.A cross-sectional study was conducted by cluster sampling in Henan province, China. Based on the level of fasting plasma glucose (FPG) and the history of T2DM, the...
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