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Article

From interaction to co-association --a Fisher r-to-z transformation-based simple statistic for real world genome-wide association study.

PloS one - 1 Jan 2013

Yuan Zhongshang, Liu Hong, Zhang Xiaoshuai, Li Fangyu, Zhao Jinghua, Zhang Furen, Xue Fuzhong

Abstract excerpt

Currently, the genetic variants identified by genome wide association study (GWAS) generally only account for a small proportion of the total heritability for complex disease. One crucial reason is the underutilization of gene-gene joint effects commonly encountered in GWAS, which includes their main effects and co-association. However, gene-gene co-association is often customarily put into the framework of...

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Identifiers

PMID: 23923021
DOI: 10.1371/journal.pone.0070774
PMCID: PMC3726765

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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