Article
Testing genetic association with rare variants in admixed populations.
Genetic epidemiology - 1 Jan 2013
Mao Xianyun, Li Yun, Liu Yichuan, Lange Leslie, Li Mingyao
Abstract excerpt
Recent studies suggest that rare variants play an important role in the etiology of many traits. Although a number of methods have been developed for genetic association analysis of rare variants, they all assume a relatively homogeneous population under study. Such an assumption may not be valid for samples collected from admixed populations such as African Americans and Hispanic Americans as there is a great...
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