Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Confounding and heterogeneity in genetic association studies with admixed populations.

American journal of epidemiology - 15 Feb 2013

Liu Jinghua, Lewinger Juan Pablo, Gilliland Frank D, Gauderman W James, Conti David V

Abstract excerpt

Association studies among admixed populations pose many challenges including confounding of genetic effects due to population substructure and heterogeneity due to different patterns of linkage disequilibrium (LD). We use simulations to investigate controlling for confounding by indicators of global ancestry and the impact of including a covariate for local ancestry. In addition, we investigate the use of an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to California
Share to Confounding Factors, Epidemiologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Heterogeneity

Share to Hispanic or Latino

Share to Linear Models

Share to Mathematical Computing

Share to Multivariate Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 23334005
DOI: 10.1093/aje/kws234
PMCID: PMC3626055

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Confounding and heterogeneity in genetic association studies with admixed populations.PMID 23334005Read ↗

Properties of global- and local-ancestry adjustments in genetic association tests in admixed populations.Semantic proximity Read ↗

Impact of cross-ancestry genetic architecture on GWASs in admixed populations.Semantic proximity Read ↗

Adjustment for local ancestry in genetic association analysis of admixed populations.Semantic proximity Read ↗

The role of local ancestry adjustment in association studies using admixed populations.Semantic proximity Read ↗

Impact of cross-ancestry genetic architecture on GWAS in admixed populationsSemantic proximity Read ↗

A robust and powerful two-step testing procedure for local ancestry adjusted allelic association analysis in admixed populations.Semantic proximity Read ↗

Detecting Heterogeneity in Population Structure Across the Genome in Admixed PopulationsSemantic proximity Read ↗

Ancestry-specific association mapping in admixed populationsSemantic proximity Read ↗

Leveraging local ancestry to detect gene-gene interactions in genome-wide data.Semantic proximity Read ↗

Causal effects on complex traits are similar across segments of different continental ancestries within admixed individualsSemantic proximity Read ↗

Admixed and single-continental genome segments of the same ancestry have distinct linkage disequilibrium patterns.Semantic proximity Read ↗

Causal effects on complex traits are similar across segments of different continental ancestries within admixed individualsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.