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Article

Admixed and single-continental genome segments of the same ancestry have distinct linkage disequilibrium patterns.

Genome biology - 11 Jul 2025

Lee Hanbin, Lee Moo Hyuk, Hou Kangcheng, Pasaniuc Bogdan, Han Buhm

Abstract excerpt

BACKGROUND: Admixed populations offer valuable insight into the genetic architecture of complex traits. Many studies have proposed methods for genome-wide association study (GWAS) in admixed populations and various simulation studies have evaluated their performances. In this work, we propose another direction of comparison of recently proposed methods for admixed GWAS from a population genetic viewpoint....

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Identifiers

PMID: 40646547
DOI: 10.1186/s13059-025-03672-w
PMCID: PMC12255047

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