Article
Joint ancestry and association testing in admixed individuals.
PLoS computational biology - 1 Dec 2011
Shriner Daniel, Adeyemo Adebowale, Rotimi Charles N
Abstract excerpt
For samples of admixed individuals, it is possible to test for both ancestry effects via admixture mapping and genotype effects via association mapping. Here, we describe a joint test called BMIX that combines admixture and association statistics at single markers. We first perform high-density admixture mapping using local ancestry. We then perform association mapping using stratified regression, wherein for...
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