Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A robust and powerful two-step testing procedure for local ancestry adjusted allelic association analysis in admixed populations.

Genetic epidemiology - 1 Apr 2018

Duan Qing, Xu Zheng, Raffield Laura M, Chang Suhua, Wu Di, Lange Ethan M, Reiner Alex P, Li Yun

Abstract excerpt

Genetic association studies in admixed populations allow us to gain deeper understanding of the genetic architecture of human diseases and traits. However, population stratification, complicated linkage disequilibrium (LD) patterns, and the complex interplay of allelic and ancestry effects on phenotypic traits pose challenges in such analyses. These issues may lead to detecting spurious associations and/or result...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Computer Simulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Pool

Share to Linkage Disequilibrium

Share to Models, Genetic

Share to Statistics as Topic

Share to Time Factors

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 29226381
DOI: 10.1002/gepi.22104
PMCID: PMC5851818

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A robust and powerful two-step testing procedure for local ancestry adjusted allelic association analysis in admixed populations.PMID 29226381Read ↗

The role of local ancestry adjustment in association studies using admixed populations.Semantic proximity Read ↗

Adjustment for local ancestry in genetic association analysis of admixed populations.Semantic proximity Read ↗

Joint ancestry and association testing in admixed individuals.Semantic proximity Read ↗

Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium.Semantic proximity Read ↗

Improved Allele Frequencies in gnomAD through Local Ancestry InferenceSemantic proximity Read ↗

Joint testing of genotype and ancestry association in admixed families.Semantic proximity Read ↗

Leveraging local ancestry to detect gene-gene interactions in genome-wide data.Semantic proximity Read ↗

Properties of global- and local-ancestry adjustments in genetic association tests in admixed populations.Semantic proximity Read ↗

Confounding and heterogeneity in genetic association studies with admixed populations.Semantic proximity Read ↗

Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power.Semantic proximity Read ↗

An ancestry-based approach for detecting interactions.Semantic proximity Read ↗

GWAS in the southern African context.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.