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Article

Detecting Multiethnic Rare Variants.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Ouyang Weiwei, Zhu Xiaofeng, Qin Huaizhen

Abstract excerpt

Genome-wide association studies have identified many common genetic variants which are associated with certain diseases. The identified common variants, however, explain only a small portion of the heritability of a complex disease phenotype. The missing heritability motivated researchers to test the hypothesis that rare variants influence common diseases. Next-generation sequencing technologies have made the...

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PMID: 28980263
DOI: 10.1007/978-1-4939-7274-6_26
PMCID: PMC6350776

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