Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

<i>CEBP</i> factors regulate telomerase reverse transcriptase promoter activity in whey acidic protein‐T mice during mammary carcinogenesis

1 Oct 2012

Abstract excerpt

Telomerase is activated in the majority of invasive breast cancers, but the time point of telomerase activation during mammary carcinogenesis is not clear. We have recently presented a transgenic mouse model to study human telomerase reverse transcriptase (TERT) gene expression in vivo (hTERTp-lacZ). In the present study, hTERTp-lacZxWAP-T bitransgenic mice were generated to analyze the mechanisms responsible for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Genetics and Reproduction
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23023397
DOI: 10.1002/ijc.27880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

<i>CEBP</i> factors regulate telomerase reverse transcriptase promoter activity in whey acidic protein‐T mice during mammary carcinogenesisPMID 23023397Read ↗

Human Specific Regulation of the Telomerase Reverse Transcriptase GeneSemantic proximity Read ↗

TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friendsSemantic proximity Read ↗

Regulation and clinical potential of telomerase reverse transcriptase (TERT/hTERT) in breast cancerSemantic proximity Read ↗

Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain.Semantic proximity Read ↗

Differential cis-regulation of human versus mouse <i>TERT</i> gene expression <i>in vivo</i> : Identification of a human-specific repressive elementSemantic proximity Read ↗

The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression.Semantic proximity Read ↗

Telomerase reactivation in cancers: Mechanisms that govern transcriptional activation of the wild-type vs. mutant TERT promoters.Semantic proximity Read ↗

Telomerase reverse transcriptase gene knock‐in unleashes enhanced longevity and accelerated damage repair in miceSemantic proximity Read ↗

Telomerase reactivation induces progression of mouse Braf <sup>V600E</sup> -driven thyroid cancers without telomere lengtheningSemantic proximity Read ↗

TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program.Semantic proximity Read ↗

TERT drives liver tumorigenesis beyond telomere elongationSemantic proximity Read ↗

TERT drives liver tumorigenesis beyond telomere elongation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.