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Regulation and clinical potential of telomerase reverse transcriptase (TERT/hTERT) in breast cancer

23 Aug 2023

Abstract excerpt

Telomerase reverse transcriptase (TERT/hTERT) serves as the pivotal catalytic subunit of telomerase, a crucial enzyme responsible for telomere maintenance and human genome stability. The high activation of hTERT, observed in over 90% of tumors, plays a significant role in tumor initiation and progression. An in-depth exploration of hTERT activation mechanisms in cancer holds promise for advancing our...

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Share to Advanced biosensing and bioanalysis techniques
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37612721
DOI: 10.1186/s12964-023-01244-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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