Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigation of host candidate malaria-associated risk/protective SNPs in a Brazilian Amazonian population.

PloS one - 1 Jan 2012

da Silva Santos Simone, Clark Taane G, Campino Susana, Suarez-Mutis Martha Cecília, Rockett Kirk A, Kwiatkowski Dominic P, Fernandes Octavio

Abstract excerpt

The Brazilian Amazon is a hypo-endemic malaria region with nearly 300,000 cases each year. A variety of genetic polymorphisms, particularly in erythrocyte receptors and immune response related genes, have been described to be associated with susceptibility and resistance to malaria. In order to identify polymorphisms that might be associated with malaria clinical outcomes in a Brazilian Amazonian population,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brazil
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to LTA gene

Share to TLR4 gene

Share to TNF gene

Share to Genetic Predisposition to Disease

Share to Malaria

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 22615793
DOI: 10.1371/journal.pone.0036692
PMCID: PMC3353949

Genes

LTA
TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of host candidate malaria-associated risk/protective SNPs in a Brazilian Amazonian population.PMID 22615793Read ↗

Genetic variants of TLR4, including the novel variant, rs5030719, and related genes are associated with susceptibility to clinical malaria in African children.Semantic proximity Read ↗

TOLLIP gene variant is associated with Plasmodium vivax malaria in the Brazilian Amazon.Semantic proximity Read ↗

IL1B, IL4R, IL12RB1 and TNF gene polymorphisms are associated with Plasmodium vivax malaria in Brazil.Semantic proximity Read ↗

Association of cytokine and Toll-like receptor gene polymorphisms with severe malaria in three regions of Cameroon.Semantic proximity Read ↗

Association of toll like receptors polymorphism (TLR1-rs4833095, TLR1-rs5743611, TLR6-rs5743810, TLR6-rs5743809, TLR4-rs4986790, TLR4-rs4986791, TLR9 rs187084) with clinical outcome of malaria among children in Ibadan, Southwest Nigeria.Semantic proximity Read ↗

Genetic variants of tumor necrosis factor-α -308G/A (rs1800629) but not Toll-interacting proteins or vitamin D receptor genes enhances susceptibility and severity of malaria infection.Semantic proximity Read ↗

Association of variants in IL1B, TLR9, TREM1, IL10RA, and CD3G and Native American ancestry on malaria susceptibility in Colombian populations.Semantic proximity Read ↗

Association of TLR variants with susceptibility to Plasmodium vivax malaria and parasitemia in the Amazon region of Brazil.Semantic proximity Read ↗

Genetic variation of TLR-4, TLR-9 and TIRAP genes in Iranian malaria patients.Semantic proximity Read ↗

A Toll-like receptor-1 variant and its characteristic cellular phenotype is associated with severe malaria in Papua New Guinean children.Semantic proximity Read ↗

Genetic association of Toll-like-receptor 4 and tumor necrosis factor-alpha polymorphisms with Plasmodium falciparum blood infection levels.Semantic proximity Read ↗

Association of candidate gene polymorphisms and TGF-beta/IL-10 levels with malaria in three regions of Cameroon: a case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.