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Article

Association of cytokine and Toll-like receptor gene polymorphisms with severe malaria in three regions of Cameroon.

PloS one - 1 Jan 2013

Apinjoh Tobias O, Anchang-Kimbi Judith K, Njua-Yafi Clarisse, Mugri Regina N, Ngwai Andre N, Rockett Kirk A, Mbunwe Eric, Besingi Richard N, Clark Taane G, Kwiatkowski Dominic P, Achidi Eric A

Abstract excerpt

P. falciparum malaria is one of the most widespread and deadliest infectious diseases in children under five years in endemic areas. The disease has been a strong force for evolutionary selection in the human genome, and uncovering the critical human genetic factors that confer resistance to the disease would provide clues to the molecular basis of protective immunity that would be invaluable for vaccine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24312262
DOI: 10.1371/journal.pone.0081071
PMCID: PMC3842328

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