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Article

Association of candidate gene polymorphisms and TGF-beta/IL-10 levels with malaria in three regions of Cameroon: a case-control study.

Malaria journal - 16 Jun 2014

Apinjoh Tobias O, Anchang-Kimbi Judith K, Njua-Yafi Clarisse, Ngwai André N, Mugri Regina N, Clark Taane G, Rockett Kirk A, Kwiatkowski Dominic P, Achidi Eric A

Abstract excerpt

BACKGROUND: Plasmodium falciparum malaria is one of the most widespread and deadliest infectious diseases in children under five years in endemic areas. The disease has been a strong force for evolutionary selection in the human genome, and uncovering the critical host genetic factors that confer resistance to the disease would provide clues to the molecular basis of protective immunity and improve vaccine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24934404
DOI: 10.1186/1475-2875-13-236
PMCID: PMC4077225

Genes

ABO
ADCY9
HBB
NOS2
RTN3

Provenance

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