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Article

Genetic association of Toll-like-receptor 4 and tumor necrosis factor-alpha polymorphisms with Plasmodium falciparum blood infection levels.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2010

Basu Madhumita, Maji Ardhendu Kumar, Chakraborty Arindom, Banerjee Rahul, Mullick Shrabanee, Saha Pabitra, Das Sonali, Kanjilal Sumana Datta, Sengupta Sanghamitra

Abstract excerpt

Dysregulated innate immune responses due to inappropriate signaling by Toll-like receptors (TLRs) and aberrant production of pro-inflammatory cytokines are implicated in the immunopathology and disease outcome in Plasmodium falciparum malaria. This study investigates the relationship between poly...

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Source

Identifiers

PMID: 20307689
DOI: 10.1016/j.meegid.2010.03.008

Genes

TNF
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20307689-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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