Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation of TLR-4, TLR-9 and TIRAP genes in Iranian malaria patients.

Malaria journal - 4 Apr 2011

Zakeri Sedigheh, Pirahmadi Sakineh, Mehrizi Akram A, Djadid Navid D

Abstract excerpt

BACKGROUND: Toll-like receptors (TLRs) recognize pathogen-associated molecular patterns and their activation leads to the induction of effector genes involving inflammatory cytokines that may have contribute to controlling parasite growth and disease pathogenesis. The current immunogenetic study was designed to analyse the key components of innate immunity, TLRs and TIRAP (Toll-interleukin-1 receptor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunity, Innate
Share to Iran
Share to Malaria, Falciparum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Glycoproteins

Share to Plasmodium falciparum

Share to Receptors, Interleukin-1

Share to Toll-Like Receptor 4

Share to Toll-Like Receptor 9

Source

Open in PubMed Open full text

Identifiers

PMID: 21457584
DOI: 10.1186/1475-2875-10-77
PMCID: PMC3079695

Genes

TIRAP
MAL
MYD88

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation of TLR-4, TLR-9 and TIRAP genes in Iranian malaria patients.PMID 21457584Read ↗

Toll-like receptor 9 and 4 gene polymorphisms in susceptibility and severity of malaria: a meta-analysis of genetic association studies.Semantic proximity Read ↗

Role of polymorphisms of toll-like receptor (TLR) 4, TLR9, toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) and FCGR2A genes in malaria susceptibility and severity in Burundian children.Semantic proximity Read ↗

Influence of common variants of TLR4 and TLR9 on clinical outcomes of Plasmodium falciparum malaria in Odisha, India.Semantic proximity Read ↗

TOLLIP gene variant is associated with Plasmodium vivax malaria in the Brazilian Amazon.Semantic proximity Read ↗

Heterozygous mutants of TIRAP (S180L) polymorphism protect adult patients with Plasmodium falciparum infection against severe disease and mortality.Semantic proximity Read ↗

Role of MyD88-adaptor-like gene polymorphism rs8177374 in modulation of malaria severity in the Pakistani population.Semantic proximity Read ↗

Toll‐like receptor polymorphism in host immune response to infectious diseases: A reviewSemantic proximity Read ↗

Association of TLR variants with susceptibility to Plasmodium vivax malaria and parasitemia in the Amazon region of Brazil.Semantic proximity Read ↗

Variants in the toll-like receptor signaling pathway and clinical outcomes of malaria.Semantic proximity Read ↗

Investigation of host candidate malaria-associated risk/protective SNPs in a Brazilian Amazonian population.Semantic proximity Read ↗

A meta-analysis of TLR4 and TLR9 SNPs implicated in severe malaria.Semantic proximity Read ↗

Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.