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Article

IL1B, IL4R, IL12RB1 and TNF gene polymorphisms are associated with Plasmodium vivax malaria in Brazil.

Malaria journal - 7 Dec 2012

Sortica Vinicius A, Cunha Maristela G, Ohnishi Maria Deise O, Souza Jose M, Ribeiro-Dos-Santos Andrea K C, Santos Ney P C, Callegari-Jacques Sídia M, Santos Sidney E B, Hutz Mara H

Abstract excerpt

BACKGROUND: Malaria is among the most prevalent parasitic diseases worldwide. In Brazil, malaria is concentrated in the northern region, where Plasmodium vivax accounts for 85% disease incidence. The role of genetic factors in host immune system conferring resistance/susceptibility against P. vivax infections is still poorly understood. METHODS: The present study investigates the influence of polymorphisms in 18...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23217179
DOI: 10.1186/1475-2875-11-409
PMCID: PMC3537609

Genes

TNF
IFNG
IFNGR1
PTPN22
VDR

Provenance

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