Article
Massively parallel haplotyping on microscopic beads for the high-throughput phase analysis of single molecules.
PloS one - 1 Jan 2012
Boulanger Jérôme, Muresan Leila, Tiemann-Boege Irene
Abstract excerpt
In spite of the many advances in haplotyping methods, it is still very difficult to characterize rare haplotypes in tissues and different environmental samples or to accurately assess the haplotype diversity in large mixtures. This would require a haplotyping method capable of analyzing the phase of single molecules with an unprecedented throughput. Here we describe such a haplotyping method capable of analyzing...
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