Article
Droplet Barcode Sequencing for targeted linked-read haplotyping of single DNA molecules.
Nucleic acids research - 27 Jul 2017
Redin David, Borgström Erik, He Mengxiao, Aghelpasand Hooman, Käller Max, Ahmadian Afshin
Abstract excerpt
Data produced with short-read sequencing technologies result in ambiguous haplotyping and a limited capacity to investigate the full repertoire of biologically relevant forms of genetic variation. The notion of haplotype-resolved sequencing data has recently gained traction to reduce this unwanted ambiguity and enable exploration of other forms of genetic variation; beyond studies of just nucleotide...
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